Dr. Caroline Fox - Researcher, Doctor and Professor

In the latest episode, we interviewed Caroline Fox, MD, MPH, the Senior Vice President of Genetics and Target Discovery at a Flagship Pioneering start-up company. There, she leads a group applying a novel method of genomics to identify drug targets. Prior to that, she was Vice President and Head of Genome and Biomarker Sciences at Merck Research Labs (MRL), where she lead a group of nearly 150 scientists to leverage genetics and biomarker science to drive drug discovery and development across the R&D pipeline.

Show Notes & Links Of Interest

  • Introduction and Bio [00:11]

  • Question: What has she done over the course of her career as a researcher and academic? [2:48]

  • Question: What is involved with being a researcher?  Of her many research accomplishments was there a specific one that she is especially proud of? [4:49]

  • Question: How has she handled setbacks over the course of her career? [6:42]

    Question: What are the hardest challenges she has faced in her career? How did she handle them?  Did she ever consider giving up? [7:59]

  • Question: Does she feel that being a woman was an advantage or disadvantage during her career? [10:12]

  • Question: What was her childhood like and how has it influenced her throughout her career?[11:07]

  • Question: What advice does she have for young people that have not yet figured out their future? [13:05]

  • Question: Does she view mentors as important? How does she recommend people find them? [14:15]

  • Question: How has she handled change throughout her career?  Is there anything she was confident on early in her career that she has changed her mind on now? [16:45]

  • Question: How has CRISPR impacted her work? [18:56]

  • Question: If her life had gone differently, what does she think she would be doing now? [20:18]

  • Question: What advice does she have for young people hoping to pursue a career as a doctor or a researcher? [21:21]

  • Question: Was there a pivotal moment in her life that brought her to where she is today? [22:39]

  • Question: What one quality or trait does she feel young girls should embrace when pursuing their dreams? [23:41]

  • Wrap up [24:33]

Caroline Fox’s Bio

Caroline Fox, MD, MPH, is currently Senior Vice President of Genetics and Target Discovery at a Flagship Pioneering start-up company. There, she leads a group applying a novel method of genomics to identify drug targets. Prior to that, she was Vice President and Head of Genome and Biomarker Sciences at Merck Research Labs (MRL), where she lead a group of nearly 150 scientists to leverage genetics and biomarker science to drive drug discovery and development across the R&D pipeline.

Prior to joining Merck, Caroline was a tenured investigator at the National Heart, Lung, and Blood Institute and Principal Investigator of the Laboratory for Metabolic and Population Health and Deputy Branch Chief of the Population Sciences Branch of the NHLBI.  There, she authored nearly 400 peer-reviewed publications, served as an Associate Editor at Circulation, and served as Vice Chair of the Functional Genomics Translational Biology Council of the American Heart Association. Caroline was inducted into the American Society for Clinical Investigation in 2012, and named on the Thomson Reuters list of “World’s Most Influential Scientific Minds” in 2014, 2015, 2016, 2017, and 2018. Caroline completed medical school at the University of Pennsylvania, and she completed her internship, residency, and endocrinology fellowship at the Brigham and Women’s Hospital in Boston, MA.

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