Artemis

Vanessa Wyche - Director of NASA's Johnson Space Center

Vanessa Wyche - Director of NASA's Johnson Space Center

Vanessa Wyche is the Director of NASA’s Johnson Space Center in Houston, the hub for U.S. human spaceflight, overseeing everything from International Space Station operations and astronaut training to the development of spacecraft and spacesuits for the Artemis moon program. She holds a B.S. in Materials Engineering and an M.S. in Bioengineering from Clemson University, and joined NASA in 1989 as a project engineer developing hardware for microgravity experiments on the Space Shuttle and later the ISS. She went on to lead a 400-person team studying how to send astronauts to Mars, served as JSC’s Deputy Director starting in 2018, and became the center’s 13th director in 2021. In 2025 she also served a stint as NASA’s Acting Associate Administrator, the agency’s highest-ranking civil servant position, before returning to lead Johnson Space Center. Under her leadership, JSC was ranked the number one best employer among Texas’s major employers by Forbes and Statista.

In this episode, Annika is joined by new co-host Josephine “Jo” Billingsley, a seventh grader from Virginia, with her own hopes of a career in space, to talk with Ms. Wyche on a particularly busy day: a spacewalk was underway outside the International Space Station as they spoke. She walks through what it actually takes to run a space center, from coordinating crew rotations and upcoming Artemis missions to the simulated Mars habitats currently testing astronauts here on Earth. She also opens up about being the only woman in her engineering branch early in her NASA career, the mentors who shaped her path, how she handles self-doubt by preparing rather than worrying, and the advice she’d give any young woman starting out: find what you’re genuinely passionate about, and let resilience carry you through the setbacks along the way.